CRISPR/Cas9, or rather the « Charpentier-Doudna method », or ChaDoMe, or CDM, or…?

maxresdefault @Broad Institute of MIT and Harvard


Paul Knoepfler, a well known stem cell scientist who is also probably the best known stem cell twitter user and blogger, wrote a piece on famous scientific names which we use every day in the lab, such as Petri dish, Bunsen burner, Southern blots (although this one is much less used these days) etc, observing that few come from female scientists.

This made me think about the indecipherable CRISPR/Cas9 method. This bizarre acronym for the best genome editing method currently available is fast becoming fashionable and very common, but no one knows its meaning (come on, who could say that it is « Clustered Regularly Interspaced Short Palindromic Repeats » without checking google). So why not call it the « Charpentier-Doudna Method » or CDM, or ChaDoMe, or whatever similar. At least it will do justice to these two fantastic female scientists…

History, or rather the Lasker-Nobel committees, will tell us whether it should be the CDZM, or ChaDoZh method, depending on whether you consider Feng Zhang as a co-inventor of the technic. And it could be fun reading students papers about the Shadow(s) method  🙂

CRISPR/Cas9, or rather the « Charpentier-Doudna method », or ChaDoMe, or CDM, or…?